copas biosort flow cytometer  (Union Biometrica)

Journal: Cyborg and Bionic Systems

Article Title: Microfluidic-Assisted Caenorhabditis elegans Sorting: Current Status and Future Prospects

doi: 10.34133/cbsystems.0011

Figure Lengend Snippet: The development of C. elegans sorting. (A) Conventional methods. (i) Manual selection. Experimenters selected worms of the same stage from mixed worm populations under a microscope to obtain synchronized populations. (ii) Egg bleaching. Reproduced with permission from . Copyright 2012 Journal of Visualized Experiments . (B) Commercial sorter. (i) Internal view of the COPAS system. Reproduced with permission from . Copyright 2006 Springer Nature. (ii) The COPAS Biosorter is used for worm sorting. Reproduced with permission from . Copyright 2018 Springer Nature. (C) Microfluidic methods. (i) Photograph of a microfluidic on-chip sorter and a single worm trapped by multiple suction channels. Reproduced with permission from . Copyright 2007 National Academy of Sciences, U.S.A. (ii) Photograph of the entire microchip with 8 individual worm selection units (1 with tubes connected). Reproduced with permission from . Copyright 2016 Royal Society of Chemistry. (iii) Photograph of the microdevice. Reproduced with permission from . Copyright 2008 Springer Nature. (iv) Photograph of the target worm in the observation chamber of the microfluidic chip. The worm is sorted by measuring the size after loading through the valve. Reproduced with permission from . Copyright 2019 IEEE.

Article Snippet: Subsequently, the commercially available flow cytometer COPAS Biosorter (Fig. A) from Union Biometrica was developed in the late 1990s.

Techniques: Selection, Microscopy, MicroChIP Assay

Journal: Cyborg and Bionic Systems

Article Title: Microfluidic-Assisted Caenorhabditis elegans Sorting: Current Status and Future Prospects

doi: 10.34133/cbsystems.0011

Figure Lengend Snippet: Commercial automatic C. elegans sorters. (A) Photograph of the commercial automatic cytometer COPAS Biosorter with the accompanying desktop computer and associated liquid containers and (B) the schematic diagram of the sorting principle. Reproduced with permission from . Copyright 2006 Springer Nature. (C) The process of automated COPAS system sorting for C. elegans . Reproduced with permission from . Copyright 2008 Springer Nature. o.d., optical density; EMS, ethyl methane sulfonate.

Article Snippet: Subsequently, the commercially available flow cytometer COPAS Biosorter (Fig. A) from Union Biometrica was developed in the late 1990s.

Techniques: Cytometry